Best Nitric Oxide Supplements for Improving Men’s Sexual Health

Why should you be looking for the best nitric oxide supplements product on the market? Because nitric oxide (N.O.) is an essential molecule when it comes to men’s sexual health.1 This molecule is produced by nearly every cell in the body, and it’s responsible for dilating blood vessels, which allows for improved blood flow and erections on demand.

Unfortunately, as men age, their natural production of nitric oxide begins to slow down. Researchers have determined that by the time a man reaches 40, his body is producing less than half of the nitric oxide that it did as a teenager. This drop in nitric oxide levels can be responsible for a slew of health concerns, including:

  • Anxiety and\or depression.
  • Lack of energy.
  • Poor concentration.
  • Memory loss.
  • High blood pressure.
  • Decreased libido.
  • Erection quality issues.

This is why it is so important for aging men to boost their depleting levels of nitric oxide. This can be accomplished in a few ways, such as changing your diet to one rich in leafy greens, working out 30-minutes a day at least three days a week, or supplementing your diet with all-natural nitric oxide boosters.2

Diet and exercise may give you a small boost in nitric oxide production, but if you want an N.O. boost that’s going to actually make a difference, long term, you’re going to want to look into nitric oxide boosting supplements.

What are Nitric Oxide Boosting Supplements?

Nitric oxide boosters are daily supplements that are either formulated with the amino acid L-Arginine or contain ingredients that boost the body’s production of L-Arginine. “What makes L-Arginine so important?”, you’re probably asking. When L-Arginine is ingested, your body converts this amino acid into nitric oxide.3

There are numerous nitric oxide boosting supplements available on the market. Today we want to focus on the N.O. boosters that are formulated especially for men who are looking to boost N.O. levels in order to improve their sexual health; specifically low libido (sex drive) and erection quality issues (the inability get or maintain an erection hard enough to penetrate your partner).

The Best Nitric Oxide Supplements for Improved Sexual Health

We’ve researched numerous nitric oxide supplements over the past few years. Some of them can be life-changing as far as improved sexual health is concerned. Others, unfortunately, are formulated so poorly that you’d be better off taking a sugar pill.

So, how are you supposed to know the difference between an effective N.O. boosting supplements and a fake? The best nitric oxide supplements on the market will:

  • Be formulated in the USA – N.O. boosters made in overseas pill-mills are loaded with fake, and sometimes dangerous, ingredients.
  • Be properly formulated – The best nitric oxide supplements will be formulated with quality ingredients in doses that actually boost N.O. levels. Poor quality N.O. boosting supplements may say they’re formulated with L-Arginine, but they’re formulated in such low dosages that it’s not effective.
  • Be guaranteed by the manufacturer – Always check for N.O. boosting supplements that are backed by a money-back guarantee. If a manufacturer won’t stand behind their product, it’s probably not worth purchasing.
  • Be clinically studied – Look for an N.O. boosting supplement whose formula and\or ingredients are clinically proven to boost nitric oxide levels. You’d be surprised how many N.O. supplements there are on the market that are formulated with cheap ingredients that don’t do anything to boost N.O. levels.

Below we’ve reviewed what we consider to be the 5 best nitric oxide supplements on the market. Each of these supplements meets all of the above requirements, and all are formulated in Current Good Manufacturing Practice (CGMP) compliant facilities.4

#1. VigRX Nitric Oxide Support

vigrx nitric oxide support

Number one on our list of the best nitric oxide supplements is VigRX Nitric Oxide Support. VigRX has been making male enhancement supplements since 2001. They focus on formulating their supplements with all-natural ingredients that are backed by science, and their Nitric Oxide Support is no different. This clinically proven formula was designed to:

  • Boost sex drive
  • Boost sexual performance
  • Boost stamina
  • Improve the ability to get and keep an erection

In addition to improving sexual health, VigRX Nitric Oxide Support has the added benefit of improving blood flow to the brain, which improves cognitive health. If you’re suffering from embarrassing erection problems, due to lack of blood flow to the penis, VigRX Nitric Oxide Support can help.

VigRX Nitric Oxide Support Ingredients

This potent N.O. booster is formulated with a proprietary blend of ingredients called Velox™. The two ingredients that make up this patented blend are:

  • L-Arginine – An amino acid that converts into nitric oxide once ingested.
  • L-Citrulline – This amino acid initially converts to L-Arginine when ingested, which then converts into nitric oxide.5

Clinical studies have shown that supplementing with both of these amino acids together produces a much larger boost in N.O. than supplementing with just one or the other.6 This is why VigRX Nitric Oxide Support is considered one of the best nitric oxide supplements on the market today.

VigRX Nitric Oxide Support Clinical Studies

Numerous clinical studies have shown that the two active ingredients in VigRX Nitric Oxide Support can improve erection quality. Let’s take a look at a couple of these studies.

L-Citrulline Supplementation Improves Erection Hardness

In this double-blind clinical study, 24 men suffering from erection quality issues were given a placebo for one month and L-citrulline for the following month. Researchers found that in the month that the men were taking L-citrulline they reported more erections, better erection quality, and more sexual intercourse than in the month they were taking the placebo.

Effect of Oral Administration of L-Arginine in men with Organic Erectile Dysfunction

In this double-blind clinical study, 50 men with confirmed cases of erectile dysfunction were given an L-Arginine supplement for 6-weeks. At the conclusion of the study, researchers determined that L-Arginine supplementation was able to significantly improve erection quality in men suffering from erectile dysfunction.

Where to Buy VigRX Nitric Oxide Support

VigRX Nitric Oxide Support can be purchased directly from the VigRX website. One bottle of this erection improving N.O. booster will cost about $2\day. Prices go down to about $1.50\day, though, if you buy in bulk. VigRX also offers a 67-day money-back guarantee should you not be 100% satisfied with the product.

#2. HyperGH14x

hypergh 14x

Coming in at number two on our list of the best nitric oxide supplements is HyperGH14x. This potent supplement is formulated with ingredients that boost both N.O. levels, as well as Human Growth Hormone (HGH) levels.7 By boosting both N.O. and HGH levels, you can expect:

  • Faster and longer-lasting erections
  • Improved sex drive
  • More stamina
  • Increased energy
  • Better results at the gym

HyperGH14x will help you shed weight, stack on lean muscle mass, and improve your overall sexual health. Just what every man in their 30s is looking for.

HyperGH14x Ingredients

HyperGH14x is formulated with 15 all-natural amino acids, botanicals, and herbals, each of which are known to boost both nitric oxide and HGH levels. Included in these ingredients is L-Arginine, which we already know is clinically proven to help with erection quality issues. In addition, HyperGH14x is also formulated with L-Lysine, which helps with erection issues and can even boost penis volume.

HyperGH14x pills also comes with a daily Acetyl Choline spray. This neurotransmitter is known to boost exercise-induced HGH by 4000%, giving you increased results at the gym.

Where to Buy HyperGH14x

HyperGH14x is not available in stores or pharmacies. You can purchase HyperGH14x, without a prescription, right from their website. One set, which includes a one month supply of both the pills and the Acetyl Choline spray, will cost around $2.66\day. Buying in bulk will bring down the price to around $2.10\day. Well worth the price for a supplement that improves both sexual and physical health.

#3. ProSolution Plus

prosolution plus

Coming in at number three on our list is ProSolution Plus. This all-natural daily supplement is formulated with ingredients that boost nitric oxide production and improve overall sexual health in men. The clinically proven ingredients in ProSolution+ will:

  • Give you fatter and harder erections that last longer
  • Significantly reduce premature ejaculation
  • Boost sex drive and stamina
  • Improve your and your partner’s sexual experience

ProSolution+ makes some pretty bold claims. Luckily for them, they’ve got clinical studies to back up each of these claims.

ProSolution+ Clinical Studies

A clinical study of ProSolution+ was published in The American Journal of Therapeutics. In this triple-blind study, 148 men with moderate erection problems, problems with premature ejaculation, and/or low interest in sex were split into two groups. One group was given the daily recommended dosage of ProSolution+ for two months. The second group was given a placebo for the same amount of time.

After 2-months, the placebo group showed almost no improvement to their sexual health. The ProSolution+ group, on the other hand, showed a:

  • 64% improvement in premature ejaculation symptoms
  • 67% improvement in erectile quality symptoms
  • 48% improvement in overall sexual function
  • 78% improvement in sexual satisfaction

There are many supplements that claim to boost overall sexual health. There aren’t too many that can prove it though with a clinical study like this.

ProSolution+ Ingredients

ProSolution+ is formulated with seven all-natural herbals, vitamins, and minerals. Each ingredient was researched and clinically proven to improve different aspects of a man’s sexual health. From boosted N.O. levels to improved erection quality to boosted sex drive, the ProSolution+ formula should be able to help any man out there who is not performing at his best in the bedroom.

Where to Buy ProSolution+

You can purchase ProSolution+ directly from their website, and it’s available without a prescription. The cost for this male enhancement supplement ranges from $2.33\day to $1.17\day, depending on whether you’re buying by the month, or in bulk. ProSolution+ also offers a money-back guarantee if you’re unhappy with your results.

#4. Volume Pills

Volume Pills

Coming in at number four on our list is the nitric oxide supplement, Volume Pills. This powerful N.O. supplement was specially formulated for guys who are suffering from erection control issues, as well as low semen volume. This doctor-approved male enhancing supplement can:

  • Improve semen volume for massive loads
  • Provide intense, mind-blowing orgasms
  • Help men achieve and maintain rock-hard erections
  • Improve male infertility
  • Boost sex drive
  • Improve overall sexual health

If you’re having issues getting or keeping it up, and you’re finishing with less than impressive cumshots, Volume Pills is exactly what you’re looking for.

Volume Pills Ingredients

Volume Pills is formulated with 12 all-natural herbals and amino acids. Each of these has been clinically tested and found to improve men’s sexual health. The ingredients include.

  • Solidilin – Improves sex drive.
  • Xi lan rou gui and Hong hua fen – Increases blood flow for better erections.
  • Ku Gua – Boosts testosterone and semen production.
  • 4, 5, 7 Trihydroxy flavone and Embilica officinalis – Improves reproductive health.
  • San guo mu – Helps orgasm control.
  • Dong Chong Xia Cao – Boosts testosterone production.
  • Zinc Gluconate – Boosts overall sexual health.
  • Ling Zhi – Boosts stamina and energy.
  • Xian Mao – An aphrodisiac that boosts erection quality.
  • Tian Men Dong – Boosts erection quality.
  • Drilizen – Boosts nitric oxide levels.
  • Fucus Vesiculosus – Boosts erection quality.

Clinical studies of the above ingredients can be found on the Volume Pills website.8

Where to Buy Volume Pills

Volume Pills can be purchased right from the manufacturer’s website. These N.O. and semen boosting pills cost around $2.15\day for a 1-month supply. Buying in bulk will bring the price down to around $1.65\day.

#5. Maxoderm


Rounding out our list of the 5 best nitric oxide supplements is Maxoderm. This all-natural male enhancer is a little different than the first four N.O. boosters. As opposed to being a daily supplement, Maxoderm is a topical cream you apply to the penis before intercourse. This topical cream will:

  • Boost nitric oxide levels
  • Stimulate blood flow for instant, rock-hard erections
  • Provide a safe, water-based lubricant
  • Make sex more enjoyable for you and your partner

If you don’t want to commit to a once-daily male enhancement supplement, but still want to boost your nitric oxide levels, Maxoderm has got you covered.

Maxoderm Ingredients

Maxoderm is formulated with herbs, amino acids, botanicals, and sexual nutrients like zinc, ginseng, maca, L-Arginine, and Muira Pauma. These ingredients work individually and synergistically to boost N.O. levels and help you to have the best sex of your life. All ingredients are 100% natural and safe for topical application.

Where to Buy Maxoderm

Maxoderm can be purchased directly from the manufacturer’s website. One bottle of Maxoderm costs around $60. Depending on how often you use it, one bottle should last you anywhere from 1-2 months. Buying multiple bottles at once will bring the price down significantly. The makers of Maxoderm are so confident you’ll love their product that they offer a 60-day money-back guarantee. If you don’t notice instant, rock-hard erections, simply return the bottle for a full refund.

Which is The Best Nitric Oxide Supplement for You?

Each of the above products is a solid N.O. booster. Which is the best nitric oxide supplement for you, though? Well, that depends on what you’re looking for.

If all you’re concerned with is boosting N.O. levels for increased libido and to improve erection quality, VigRX Nitric Oxide Support is the best supplement for the job.

If you’re interested in boosting N.O. and HGH for sexual health and better results at the gym, HyperGH14x is just what you’re looking for.

If you’re looking to boost nitric oxide levels for better erection quality, and you suffer from premature ejaculation, you’ll want to give ProSolution+ a closer look.

If you’re suffering from erection control issues and low semen volume, Volume Pills will be able to help you out.

If you’re looking for a topical solution to boost your N.O. levels and improve erection quality, Maxoderm is the right lube for the job.


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  2. “5 Health Benefits of Nitric Oxide Supplements – Healthline.” 25 Mar. 2018,
  3. “Enzymes of the L-Arginine to Nitric Oxide Pathway | The ….” 1 Oct. 2004,
  4. “Facts About the Current Good Manufacturing Practices ….” 25 Jun. 2018,
  5. “Erectile Dysfunction and L-Citrulline: What You Should Know.” 28 Jun. 2017,
  6. “The Effects of Oral l-Arginine and l-Citrulline Supplementation ….” 22 Jul. 2019,
  7. “11 Ways to Boost Human Growth Hormone (HGH) Naturally.” 23 Sep. 2019,
  8. “Volume Pills Ingredients –”